Cardiovascular Disease

Cardiovascular diseases include heart and blood vessel problems that include cerebrovascular illness, coronary heart disease, rheumatic heart disease, and others. It is one of the leading causes of morbidity and mortality worldwide. Hypertension is an extremely major risk factor for cardiovascular disease.

Benefits of Ganoderma Lucidum

Some of the beneficial roles played by Ganoderma lucidum are; Polysaccharide and peptide complexed compounds have a protective effect on human endothelial cells in blood vessels. In clinical trials involving individuals with the primary stage of hypertension, normalization of blood pressure was achieved after 2 months of G. lucidum extract administration. Other research found that G. lucidum extract lowered blood lipid levels and prevented the development of atherosclerosis in rats. Clinical studies have demonstrated the effects of G. lucidum on high blood pressure in humans, and their findings dramatically decreased blood pressure when compared to placebos. The powder form of the fruiting bodies of G. lucidum considerably reduced the systolic blood pressure of the spontaneously hypertensive rats (SHR) after the 4-week feeding period. G. lucidum compounds reduced the risk of heart disease by lowering blood levels of triglycerides and cholesterol, lowering blood platelet adhesion, and normalizing blood pressure.

References

Yang L-J, You Y-H, Lin Z-B, Lin Y-F. Protective effects of Ganodermalucidum polysaccharides peptide on human umbilical vein endothelial cells injury by reactive oxygen species. Chin Pharmacol Bull 2010; 26(5):657-660. Jin H, Zhang G, Cao X, Zhang M, Long J, Luo B et al. Treatment of hypertension by Linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure microcirculation. In: Microcirculatory Approach to Asian Traditional Medicine: Strategy for the Scientific Evaluation. Excerpta Medica, International Congress Series Elsevier, Amsterdam, NY, 1996:131-138. Wang Z, Gu H, Yi S. Molecular mechanisms of Taishan Ganoderma lucidum amylose in prevention of rat atherosclerosis. Chin J Pathophysiol 2009; 25(12):2310-2313. Kabir, Y., Kimura, S., Tamura, T., 1988. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J. Nutr. Sci. Vitaminol. 34 (4), 433–443. Spence JD (2018) Controlling resistant hypertension. Stroke Vasc Neurol 3:69–75. Lin, J.M., Lin, C.C., Chen, M.F., Ujiie, T., Takada, A., 1995. Radical scavenger and antihepatotoxic activity of Ganoderma formosanum, Ganoderma lucidum and Ganoderma neo-japonicum. J. Ethnopharmacol. 47 (1), 33–41.