Antioxidant activity of G. lucidum

Several antioxidant experiments demonstrated the antioxidant activity of polysaccharides and polysaccharide complexes extracted from G.lucidum. Various in-vitro antioxidant assays confirmed the antioxidant potential. The G. lucidum polysaccharides demonstrated an antioxidant influence in in-vitro investigations. They enhanced the activity of antioxidant enzymes (SOD, CAT, and GPx) and reduced the production of IL-1, IL-6, and TNF in rats with cervical cancer. The extract of G. lucidum exhibited significant antioxidant and lipid peroxidation inhibitory action. Polysaccharides extracted from G. lucidum have antioxidant action and protect tissues against the toxicity of reactive oxygen species. They also contribute to the body's oxidative condition . The methanolic extracts isolated from G. lucidum have been demonstrated to prevent kidney damage by restoring the kidneys' antioxidant defense system. G. lucidum polysaccharides raised the number of white blood cells and lymphocytes. Serum IgG and IgA immunoglobulin amounts were also measured, and increased IgA levels were found . A study examined natural polysaccharides and degraded polysaccharides by the ultrasonic process and analyzed their hypolipidemic and antioxidant properties. G. lucidum polysaccharides have been found to exhibit biological activity against superoxide dismutase and glutathione peroxidase. Polysaccharides from G. lucidum have been demonstrated to boost non-enzymatic and enzymatic antioxidants, serum insulin levels, and lipid peroxidation. According to one study, the terpene fraction had the most antioxidants: ganoderic acids A, B, C, and D, lucidic acid B, and ganodermanontriol. G. lucidum promotes for the protection of cellular constituents from oxidative damage in order to reduce the potential of mutation and carcinogenesis. G. lucidum, substances, especially polysaccharides and triterpenoids, exhibit antioxidant action. Polysaccharides mainly guard immune cells and DNA from oxidative damage.

References

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